Pharma scrambles to fast-track drugs

Invited Talk: Fast Track to Disease-Specific Drugs? The Impact of In-Situ Proteomics Imaging (Toponomics)

Fast track to the medial prefrontal cortex.

Paul W. Frankland*†‡ and Bruno Bontempi§ *Programs in Integrative Biology and Brain and Behaviour, Hospital for Sick Children, Toronto, ON, Canada M5G 1X8; †Department of Physiology and Institute of Medical Science, University of Toronto, Toronto, ON, Canada M5S 1A8; and §Laboratoire de Neurosciences Cognitives, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5106, Univer...

The fast track to multidrug resistance.

In this issue of Molecular Cell, Kohanski et al. (2010) demonstrate that even subinhibitory concentrations of bactericidal antibiotics result in the generation of reactive oxygen species, leading to an increase in mutation rate and the emergence of multidrug-resistant bacterial strains.

The Fast Track to Cardiovascular Disease?

Air pollution is a ubiquitous environmental exposure that threatens the health of people worldwide, in no small part due to the development and exacerbation of cardiovascular diseases. Daily fluctuations in pollution have been associated with acute changes in subclinical measures of disease (eg, systemic inflammation, endothelial dysfunction, and vasoconstriction), and increases in risk of over...

Fast-track ‘coloured’ inversion

Inversion of seismic data to Acoustic Impedance is usually seen as a specialist activity, so despite the publicised benefits, inverted data are only used in a minority of cases. To help overcome this obstacle we aimed to develop a new algorithm which would not necessarily be best in class, but would be quick and easy to use and increase the use of inversion products within BPA. This new techniq...